Praktikum Bioinformatics 'Protein Structure and Function Analysis'



Praktikum (10 SWS)




Master Bioinformatics


Dr. Andrea Schafferhans, Dr. Mark Offman, Dr. Edda Kloppmann


Monday, 14.02.11, 13:00, room 01.09.034 


Tuesday 10-11:30; first meeting: Tuesday, 10.5.


Meetings: seminar room 01.09.034; Work: Praktikum room 01.08.021



Preliminary discussion and Registration

There will be a preliminary discussion (see above). There, we will give a general overview of the course and recommend reading material. 

Since we now have reached the maximum number of participants, registration is closed. If for some reason you absolutely need to take part in this particular course, discuss this by mail with Andrea Schafferhans (surname at



This year, the practical will be focussed around analysis and prediction of the effects of disease-causing mutations in the human genome. To this end, we will apply sequence analysis methods, structure prediction and molecular dynamics methods. Participants will learn the theoretical basis of the methods, how to apply them in practice and how to interpret and validate the results. 

All of this can and should be driven by the interest of the participants. We hope to incite our pariticipants' curiosity and would like to support their quest for answers to the questions they decide to address.

The students will build a wiki, where they collect all information relevant to the studied diseases and where they document the methods used and the obtained results.

Criteria to pass

At least one 15 min presentation about a method used for structure and fuction prediction. Reports and wiki pages about the tasks performed during the practical.